Dr. Alexandre Marques
Page Content
Assistant Professor
Bio
Dr. Marques obtained his Ph.D. in microbiology and immunology from the University of Sao Paulo, Brazil, in 2007, and his post-doctoral degree at the University of Texas (2007-2013). His previous positions include serving as Assistant Professor at the Federal University of Minas Gerais, Brazil, (2013-2022), Visiting Professor at Georgia Institute of Technology in 2017 and Principal Research Scientist at Georgia Tech (2018-2023).
The Marques Laboratory performs research on the biology of several endo- and ectoparasites.
The lab is focused on developing a vaccine against protozoa parasites and tick diseases.
They explore carbohydrates (αGal) and peptides from the pathogen surface to display
on Virus-like particles for vaccine development. The Marques Lab is also focused on
developing a red meat allergy and anti-tick vaccine. Bioinformatics, immunology, biochemistry
and molecular biology are used to explore new vaccine targets.
PhD. - University of Sao Paulo (2007)
B.S. - Pharmacy Federal University of Alfenas (1999)
BSC 283
- Rodrigues da Cunha GM, Azevedo MA, Nogueira DS, Clímaco MC, Valencia Ayala E, Jimenez
Chunga JA, La Valle RJY, da Cunha Galvão LM, Chiari E, Brito CRN, Soares RP, Nogueira
PM, Fujiwara RT, Gazzinelli R, Hincapie R, Chaves CS, Oliveira FMS, Finn MG, Marques
AF. α-Gal immunization positively impacts Trypanosoma cruzi colonization of heart
tissue in a mouse model.
PLoS Negl Trop Dis. 2021 Jul 27;15(7):e0009613. doi: 10.1371/journal.pntd.0009613. eCollection 2021 Jul. - Ayala EV, Rodrigues da Cunha G, Azevedo MA, Calderon M, Jimenez J, Venuto AP, Gazzinelli
R, Lavalle RJY, Riva AGV, Hincapie R, Finn MG, Marques AF.C57BL/6 α-1,3-Galactosyltransferase
Knockout Mouse as an Animal Model for Experimental Chagas Disease.
ACS Infect Dis. 2020 Jul 10;6(7):1807-1815. doi: 10.1021/acsinfecdis.0c00061. Epub 2020 May 18. PMID: 32374586 - Anna Paula V. Moura, Luiza C. B. Santos, Carlos Ramon Nascimento Brito, Edward Valencia,
Caroline Junqueira, Adalberto A. P. Filho, Mauricio R. V. Sant’Anna, Nelder F. Gontijo,
Daniella C. Bartholomeu, Ricardo T. Fujiwara, Ricardo T. Gazzinelli, Craig S. McKay,
Carlos A. Sanhueza, M. G. Finn, and Alexandre Ferreira Marques*
Virus-like Particle Display of the α‑Gal Carbohydrate for Vaccination against Leishmania Infection.
ACS Cent. Sci., September 13, 2017. DOI: 10.1021/acscentsci.7b00311. - Brito, Carlos Ramon Nascimento; Mckay, Craig S.; Azevedo, Maíra Araújo; Santos, Luíza
Costa Brandão; Venuto, Ana Paula; Nunes, Daniela Ferreira; D’Ávila, Daniella Alchaar;
Rodrigues Da Cunha, Gisele Macedo; Almeida, Igor Correia ; Gazzinelli, Ricardo Tostes
; Galvão, Lucia Maria Cunha ; Chiari, Egler; Sanhueza, Carlos A. ; Finn, M. G.; Marques,
Alexandre Ferreira.,
Virus-like Particle Display of the α-Gal Epitope for the Diagnostic Assessment of Chagas Disease.
ACS Infectious Diseases v. 2, p. 917-922, 2016. - Araujo RN, Franco PF, Rodrigues H, Santos LC, McKay CS, Sanhueza CA, Brito CR, Azevedo
MA, Venuto AP, Cowan PJ, Almeida IC, Finn M.G, Marques A.F.
Amblyomma sculptum tick saliva: α-Gal identification, antibody response and possible association with red meat allergy in Brazil. Int J Parasitol. 2016 Mar;46(3):213-20. doi: 10.1016/j.ijpara.2015.12.005. Epub 2016 Jan 23. PMID: 26812026
To view the complete list of Dr. Marques' publications, click here.
Follow Us on Social Media
